ABSTRACT
Background: Poisoning cases is a significant contributor to mortality and morbidity all over the world. Acute poisoning cases form one of the commonest causes of emergency hospital admissions. Material and methods: It is a retrospective study of 106 poisoning cases admitted in M.A.P.I.M.S., which is a tertiary health care centre in Tamil Nadu, India from January 2010 to December 2012. Results: The incidence of poisoning was highest in the age range from 20-50 years. Most common poison was insecticide/ rodenticide and cases were mostly suicidal in nature. Conclusion: Trends of poisoning cases in melmaruvathur region of Tamil Nadu are more or less similar to other parts of India.
ABSTRACT
From January 1990 to December 2000, 202 patients with clinical evidence of liver disease underwent fine needle aspiration cytology of the liver. Of these, 102 patients were diagnosed as non-neoplastic lesions. These include diffuse parenchymal disease of liver, liver abscess, hepatitis, and granulomas. There were 100 patients with malignancies of the liver. Out of the above, 64 were due to metastatic carcinoma, 31 were primary hepatocellular carcinoma, 1 hepatoblastoma and in 4 patients the diagnosis of non-Hodgkin's lymphoma was made. By comparing with clinical and biochemical parameters, the diagnostic accuracy of the fine needle aspiration cytology, in this study, was found to be more accurate in malignant nodules of the liver as compared to other pathological lesion. The findings of fine needle aspiration cytology of the liver reported by other authors are discussed and it is concluded that this diagnostic method is a safe, useful and economic procedure with minimum complication and can be routinely done for assisting diagnosis of liver diseases in our clinical set up.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Biopsy, Needle , Child , Child, Preschool , Female , Humans , Infant , Liver Diseases/pathology , Male , Middle Aged , Reproducibility of ResultsABSTRACT
The possibility of using specific polyclonal antibodies for effective site specific drug targeting to malaria infected erythrocytes has been examined. For this purpose, rabbit polyclonal antiserum was raised against Plasmodium berghei infected mouse erythrocytes (IRBC) and extensively absorbed with normal erythrocytes (NRBC). Absorbed antiserum specifically recognized IRBC. F(ab')2-fragments of these antibodies were coupled to chloroquine (chq) laden liposomes. These immunoliposomes when tested in vivo significantly suppressed malarial infection in mice.